Selective data segment monitoring system

High speed data monitoring apparatus is described for displaying the bit pattern of a selected portion of a block of transmitted data comprising a shift register for receiving the transmitted data and for temporarily containing the consecutive data bits. A programmable sync detector for monitoring the contents of the shift register and for generating a sync signal when the shift register contains a predetermined sync code is included. A counter is described for counting the data bits input to the shift register after the sync signal is generated and for generating a count complete signal when a selected number of data bits have been input to the register. A data storage device is used for storing the contents of the shift register at the time the count complete signal is generated

High-speed data word monitor

Small, portable, self-contained device provides high-speed display of bit pattern or any selected portion of transmission, can suppress filler patterns so that display is not updated, and can freeze display so that specific event may be observed in detail

Small gain theorems for large scale systems and construction of ISS Lyapunov functions

We consider interconnections of n nonlinear subsystems in the input-to-state stability (ISS) framework. For each subsystem an ISS Lyapunov function is given that treats the other subsystems as independent inputs. A gain matrix is used to encode the mutual dependencies of the systems in the network. Under a small gain assumption on the monotone operator induced by the gain matrix, a locally Lipschitz continuous ISS Lyapunov function is obtained constructively for the entire network by appropriately scaling the individual Lyapunov functions for the subsystems. The results are obtained in a general formulation of ISS, the cases of summation, maximization and separation with respect to external gains are obtained as corollaries.Comment: provisionally accepted by SIAM Journal on Control and Optimizatio

Comment to "Observation of the neutron radiative decay" by R.U. Khafizov et al., published in JETP Letters 83 (2006) 5 (Pis'ma v ZhETF 83 (2006) 7)

The commented manuscript was submitted for publication without informing at least four of the other authors, viz. N. Severijns, O. Zimmer, H.-F. Wirth and D. Rich. This violates our rights as collaborators. The analysis presented and the manuscript itself have not been discussed and have also not been approved by the entire collaboration prior to submission. Besides this formal incorrectness, we also criticise the content of the paper

Sprunggelenkarthrodese nach gescheiterter Endoprothesenimplantation

Zusammenfassung: Trotz anatomischer und biomechanischer Verbesserungen bleibt die Langzeitprognose oberer Sprunggelenkendoprothesen hinsichtlich der Überlebensrate problematisch. Bei fehlgeschlagener oberer Sprunggelenkendoprothesenimplantation stellt die Konversion in eine obere Sprunggelenkarthrodese eine zuverlässige Behandlungsmethode dar. Trotzdem ist die Durchführung aufgrund der Knochendefekte, des prekären Weichteilzustands und auch Erhaltung der Beinlänge technisch anspruchsvoll und aufwendig. Es besteht das Potenzial zu erheblichen Einschränkungen der Lebensqualität als auch Gesamtfunktion des Fuß- und Sprunggelenks. Der vorliegende Artikel behandelt das Thema der Arthrodese nach gescheiterter oberer Sprunggelenkendoprothesenimplantation und schlägt Algorithmen für die Therapie vo

Drugs for neglected diseases: a failure of the market and a public health failure?

Infectious diseases cause the suffering of hundreds of millions of people, especially in tropical and subtropical areas. Effective, affordable and easy-to-use medicines to fight these diseases are nearly absent. Although science and technology are sufficiently advanced to provide the necessary medicines, very few new drugs are being developed. However, drug discovery is not the major bottleneck. Today's R&D-based pharmaceutical industry is reluctant to invest in the development of drugs to treat the major diseases of the poor, because return on investment cannot be guaranteed. With national and international politics supporting a free market-based world order, financial opportunities rather than global health needs guide the direction of new drug development. Can we accept that the dearth of effective drugs for diseases that mainly affect the poor is simply the sad but inevitable consequence of a global market economy? Or is it a massive public health failure, and a failure to direct economic development for the benefit of society? An urgent reorientation of priorities in drug development and health policy is needed. The pharmaceutical industry must contribute to this effort, but national and international policies need to direct the global economy to address the true health needs of society. This requires political will, a strong commitment to prioritize health considerations over economic interests, and the enforcement of regulations and other mechanisms to stimulate essential drug development. New and creative strategies involving both the public and the private sector are needed to ensure that affordable medicines for today's neglected diseases are developed. Priority action areas include advocating an essential medicines R&D agenda, capacity-building in and technology transfer to developing countries, elaborating an adapted legal and regulatory framework, prioritizing funding for essential drug development and securing availability, accessibility, distribution and rational use of these drugs

Revisiting the assessment of tremor: clinical review

Tremor, an involuntary, rhythmic, and oscillatory movement of a body part, is a frequent presenting symptom to general practice and by far the most common movement disorder presentation, impacting up to 15% of such cases.1 A common initial pattern is symmetric upper-limb involvement during posture and action. Although patients are often worried about Parkinson’s disease (PD), PD tremor usually has easily recognisable features.2 This concern tends to lead to frequent referrals for specialist input despite an alternative diagnosis being more likely in a majority of cases. Essential tremor (ET) is the most common diagnosis given to patients with this presentation, which is estimated to affect 0.4–6.0% of the general population.3 This may be an overestimate as the rubric of ET and the relationship between clinical features and underlying pathophysiology is uncertain. These aspects also potentially contribute to variable diagnostic and treatment outcomes.4 A recent Movement Disorder Society consensus on phenotyping charts a course towards more precise classification.5 This will not only be useful for research but also help in clarifying common clinical syndromes seen in everyday practice. This article outlines an approach to upper-limb tremor presentations in adult patients, developing a previously proposed three cardinal question method for neck pain6 while highlighting salient aspects of the consensus statement that could potentially aid in clinical stratification of cases

Observation of Landau quantization and standing waves in HfSiS

Recently, HfSiS was found to be a new type of Dirac semimetal with a line of Dirac nodes in the band structure. Meanwhile, Rashba-split surface states are also pronounced in this compound. Here we report a systematic study of HfSiS by scanning tunneling microscopy/spectroscopy at low temperature and high magnetic field. The Rashba-split surface states are characterized by measuring Landau quantization and standing waves, which reveal a quasi-linear dispersive band structure. First-principles calculations based on density-functional theory are conducted and compared with the experimental results. Based on these investigations, the properties of the Rashba-split surface states and their interplay with defects and collective modes are discussed.Comment: 6 pages, 5 figure

Local Guarantees in Graph Cuts and Clustering

Correlation Clustering is an elegant model that captures fundamental graph cut problems such as Min $s-t$ Cut, Multiway Cut, and Multicut, extensively studied in combinatorial optimization. Here, we are given a graph with edges labeled $+$ or $-$ and the goal is to produce a clustering that agrees with the labels as much as possible: $+$ edges within clusters and $-$ edges across clusters. The classical approach towards Correlation Clustering (and other graph cut problems) is to optimize a global objective. We depart from this and study local objectives: minimizing the maximum number of disagreements for edges incident on a single node, and the analogous max min agreements objective. This naturally gives rise to a family of basic min-max graph cut problems. A prototypical representative is Min Max $s-t$ Cut: find an $s-t$ cut minimizing the largest number of cut edges incident on any node. We present the following results: $(1)$ an $O(\sqrt{n})$-approximation for the problem of minimizing the maximum total weight of disagreement edges incident on any node (thus providing the first known approximation for the above family of min-max graph cut problems), $(2)$ a remarkably simple $7$-approximation for minimizing local disagreements in complete graphs (improving upon the previous best known approximation of $48$), and $(3)$ a $1/(2+\varepsilon)$-approximation for maximizing the minimum total weight of agreement edges incident on any node, hence improving upon the $1/(4+\varepsilon)$-approximation that follows from the study of approximate pure Nash equilibria in cut and party affiliation games